What is Thapsigargin? Frequently Asked Questions
Differential impact of imipramine on thapsigargin- and tunicamycin-induced endoplasmic reticulum stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells - ScienceDirect
Frontiers | STING, the Endoplasmic Reticulum, and Mitochondria: Is Three a Crowd or a Conversation?
Endoplasmic reticulum stress signalling – from basic mechanisms to clinical applications - Almanza - 2019 - The FEBS Journal - Wiley Online Library
Molecules | Free Full-Text | Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics
Thapsigargin: key to new host-directed coronavirus antivirals?: Trends in Pharmacological Sciences
Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation | Journal of Experimental & Clinical Cancer Research | Full Text
Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response - Journal of Molecular and Cellular Cardiology
Kinetics of Thapsigargin- Ca2+-ATPase (Sarcoplasmic Reticulum) Interaction Reveals a Two-step Binding Mechanism and Picomolar Inhibition * - Journal of Biological Chemistry
MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System | eNeuro
Cells | Free Full-Text | Calcium Pathways in Human Neutrophils—The Extended Effects of Thapsigargin and ML-9
Endoplasmic reticulum stress stimulates the release of extracellular vesicles carrying danger-associated molecular pattern (DAMP) molecules | Oncotarget
Frontiers | The Cross-Links of Endoplasmic Reticulum Stress, Autophagy, and Neurodegeneration in Parkinson's Disease
Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4–CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA | Journal of Neuroscience
Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation | Scientific Reports
Pancreatic INS-1 β-Cell Response to Thapsigargin and Rotenone: A Comparative Proteomics Analysis Uncovers Key Pathways of β-Cell Dysfunction | Chemical Research in Toxicology
Proteomic Signatures in Thapsigargin-Treated Hepatoma Cells | Chemical Research in Toxicology
IJMS | Free Full-Text | Thapsigargin—From Traditional Medicine to Anticancer Drug
Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1 | Aging
Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway - ScienceDirect
Diabetes Alters Intracellular Calcium Transients in Cardiac Endothelial Cells | PLOS ONE
IJMS | Free Full-Text | Valproate Attenuates Endoplasmic Reticulum Stress-Induced Apoptosis in SH-SY5Y Cells via the AKT/GSK3β Signaling Pathway
Thapsigargin | SERCA ATPase Inhibitor | Tocris Bioscience
